J.B. Verlooy, jurist, taalflamingant en politicus (1746-1797)

JB Commentary

Advances in stem cell biology have clarified that a tumour is a collection of heterogeneous cell populations, and that only a small fraction of tumour cells possesses the potential to self-renew. Delta-like 1 protein (Dlk-1) is a surface antigen present on foetal hepatic stem/progenitor cells but absent from mature hepatocytes in neonatal and adult rodent liver. Using a monoclonal antibody (mAb...

JB Khadka

C4an01853b 1791..1797 ++

Fast infrared mapping with sub-millimeter lateral resolution as well as time-resolved infrared studies of kinetic processes of functional organic thin films require a new generation of infrared ellipsometers. We present a novel laboratory-based infrared (IR) laser mapping ellipsometer, in which a laser is coupled to a variableangle rotating analyzer ellipsometer. Compared to conventional Fourie...

[Cayetano Heredia (1797-1861)].

En la historia de la medicina peruana podemos encontrar diversos ejemplos de destacados científicos, ilustres divulgadores de la ciencia, devotos practicantes de su arte, muchos de los cuales han recibido público reconocimiento por su obra científica. También encontramos aquellos que, paralelo a su ejercicio profesional, han tenido una activa vida ciudadana e intelectual, por lo cual también ha...

Dmd053082 1797..1804

Aldehyde oxidase 1 (AOX1) is a cytosolic enzyme highly expressed in liver and plays a key role in metabolizing drugs containing aromatic azaheterocyclic substituents. Rapid metabolism catalyzed by AOX1 can cause a drug to exhibit high clearance, low exposure, and hence decreased efficacy or even increased toxicity (if AOX1 generated metabolites are toxic). There is a need to develop the correla...